node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGT87252.1 | KGT95535.1 | NG99_23740 | NG99_03085 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.896 |
KGT87252.1 | KGT95820.1 | NG99_23740 | NG99_01370 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
KGT87252.1 | clpS | NG99_23740 | NG99_09920 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.852 |
KGT87252.1 | dnaJ | NG99_23740 | NG99_21960 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.613 |
KGT87252.1 | dnaK | NG99_23740 | NG99_21965 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.771 |
KGT87252.1 | grpE | NG99_23740 | NG99_14225 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.789 |
KGT93293.1 | KGT95535.1 | NG99_11520 | NG99_03085 | Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.895 |
KGT93293.1 | KGT95820.1 | NG99_11520 | NG99_01370 | Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.466 |
KGT93293.1 | dnaJ | NG99_11520 | NG99_21960 | Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.623 |
KGT93293.1 | dnaK | NG99_11520 | NG99_21965 | Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.466 |
KGT95508.1 | KGT95535.1 | NG99_03080 | NG99_03085 | Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.899 |
KGT95535.1 | KGT87252.1 | NG99_03085 | NG99_23740 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | 0.896 |
KGT95535.1 | KGT93293.1 | NG99_03085 | NG99_11520 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.895 |
KGT95535.1 | KGT95508.1 | NG99_03085 | NG99_03080 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
KGT95535.1 | KGT95820.1 | NG99_03085 | NG99_01370 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
KGT95535.1 | clpP | NG99_03085 | NG99_06445 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.918 |
KGT95535.1 | clpS | NG99_03085 | NG99_09920 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.898 |
KGT95535.1 | dnaJ | NG99_03085 | NG99_21960 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.824 |
KGT95535.1 | dnaK | NG99_03085 | NG99_21965 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
KGT95535.1 | grpE | NG99_03085 | NG99_14225 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.875 |