STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGT94304.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)    
Predicted Functional Partners:
rutB
Amidohydrolase; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily.
 
 
  0.938
KGT94650.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.877
rutA
Pyrimidine monooxygenase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate.
  
  
 
0.838
KGT94427.1
Flavoprotein oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.814
rutD
Aminoacrylate hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
 
    0.765
KGT94206.1
NAD(P)H-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.744
KGT93068.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.698
KGT92913.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.698
rutE
Malonic semialdehyde reductase; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted.
 
  
 0.610
KGT94300.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
       0.551
Your Current Organism:
Erwinia typographi
NCBI taxonomy Id: 371042
Other names: DSM 22678, E. typographi, Erwinia sp. DSM 22678, Erwinia sp. DSM 24222, Erwinia sp. DSM 24223, Erwinia sp. Y4, Erwinia sp. Y7, Erwinia typographi Skrodenyte-Arbaciauskiene et al. 2012, LMG 25347, LMG:25347, Pantoea sp. Y1, strain Y1
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