STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGT92993.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)    
Predicted Functional Partners:
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.840
KGT92992.1
2-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.781
fadJ
Multifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
  0.741
fadB
Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
  0.741
KGT92991.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.695
KGT92990.1
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 3 family.
  
    0.595
KGT86477.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.502
KGT92238.1
Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.483
KGT88925.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.473
KGT92988.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.470
Your Current Organism:
Erwinia typographi
NCBI taxonomy Id: 371042
Other names: DSM 22678, E. typographi, Erwinia sp. DSM 22678, Erwinia sp. DSM 24222, Erwinia sp. DSM 24223, Erwinia sp. Y4, Erwinia sp. Y7, Erwinia typographi Skrodenyte-Arbaciauskiene et al. 2012, LMG 25347, LMG:25347, Pantoea sp. Y1, strain Y1
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