node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGT86653.1 | KGT88039.1 | NG99_24905 | NG99_22315 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.754 |
KGT86653.1 | KGT91857.1 | NG99_24905 | NG99_15955 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | ABC transporter permease; Involved in maintaining OM lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
KGT86653.1 | KGT94218.1 | NG99_24905 | NG99_10235 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Membrane protein; OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.945 |
KGT86653.1 | KGT94468.1 | NG99_24905 | NG99_07510 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.770 |
KGT86653.1 | KGT95002.1 | NG99_24905 | NG99_04990 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Universal stress global response regulator UspA; Involved in resistance to DNA-damaging agents; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |
KGT86653.1 | KGT95823.1 | NG99_24905 | NG99_01395 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Membrane assembly protein AsmA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.763 |
KGT86653.1 | ftsN | NG99_24905 | NG99_03885 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.765 |
KGT86653.1 | lpoB | NG99_24905 | NG99_00805 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Penicillin-binding protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. | 0.775 |
KGT86653.1 | tolB | NG99_24905 | NG99_18755 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.926 |
KGT86653.1 | zapB | NG99_24905 | NG99_03860 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.773 |
KGT88039.1 | KGT86653.1 | NG99_22315 | NG99_24905 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | 0.754 |
KGT88039.1 | KGT94218.1 | NG99_22315 | NG99_10235 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Membrane protein; OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | 0.814 |
KGT88039.1 | KGT94468.1 | NG99_22315 | NG99_07510 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
KGT88039.1 | KGT95823.1 | NG99_22315 | NG99_01395 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Membrane assembly protein AsmA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.664 |
KGT88039.1 | ftsN | NG99_22315 | NG99_03885 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.476 |
KGT88039.1 | lpoB | NG99_22315 | NG99_00805 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Penicillin-binding protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. | 0.728 |
KGT88039.1 | tolB | NG99_22315 | NG99_18755 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.905 |
KGT88039.1 | zapB | NG99_22315 | NG99_03860 | Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.420 |
KGT91857.1 | KGT86653.1 | NG99_15955 | NG99_24905 | ABC transporter permease; Involved in maintaining OM lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | 0.832 |
KGT94218.1 | KGT86653.1 | NG99_10235 | NG99_24905 | Membrane protein; OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Gram-negative porin family. | 0.945 |