KGT86251.1 protein (Erwinia typographi) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

KGT86251.1

Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)

Predicted Functional Partners:

KGT86252.1

0.604

KGT86254.1

0.509

KGT86255.1

0.507

KGT86253.1

0.494

KGT86256.1

0.494

KGT86272.1

0.494

KGT86249.1

0.439

KGT86250.1

0.439

Your Current Organism:

Erwinia typographi

NCBI taxonomy Id: 371042
Other names: DSM 22678, E. typographi, Erwinia sp. DSM 22678, Erwinia sp. DSM 24222, Erwinia sp. DSM 24223, Erwinia sp. Y4, Erwinia sp. Y7, Erwinia typographi Skrodenyte-Arbaciauskiene et al. 2012, LMG 25347, LMG:25347, Pantoea sp. Y1, strain Y1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGT86249.1	KGT86250.1	NG99_26160	NG99_26165	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.934
KGT86249.1	KGT86251.1	NG99_26160	NG99_26170	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.439
KGT86250.1	KGT86249.1	NG99_26165	NG99_26160	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.934
KGT86250.1	KGT86251.1	NG99_26165	NG99_26170	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.439
KGT86251.1	KGT86249.1	NG99_26170	NG99_26160	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.439
KGT86251.1	KGT86250.1	NG99_26170	NG99_26165	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.439
KGT86251.1	KGT86252.1	NG99_26170	NG99_26175	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604
KGT86251.1	KGT86253.1	NG99_26170	NG99_26180	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	HK97 gp10 family phage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
KGT86251.1	KGT86254.1	NG99_26170	NG99_26185	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.509
KGT86251.1	KGT86255.1	NG99_26170	NG99_26190	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Head-tail adaptor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.507
KGT86251.1	KGT86256.1	NG99_26170	NG99_26195	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
KGT86251.1	KGT86272.1	NG99_26170	NG99_26200	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
KGT86252.1	KGT86251.1	NG99_26175	NG99_26170	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604
KGT86252.1	KGT86253.1	NG99_26175	NG99_26180	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	HK97 gp10 family phage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
KGT86252.1	KGT86254.1	NG99_26175	NG99_26185	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.674
KGT86252.1	KGT86255.1	NG99_26175	NG99_26190	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Head-tail adaptor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.672
KGT86252.1	KGT86256.1	NG99_26175	NG99_26195	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
KGT86252.1	KGT86272.1	NG99_26175	NG99_26200	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
KGT86253.1	KGT86251.1	NG99_26180	NG99_26170	HK97 gp10 family phage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
KGT86253.1	KGT86252.1	NG99_26180	NG99_26175	HK97 gp10 family phage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Major tail shaft subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901607

Alpha-amino acid biosynthetic process

6 of 81

1.39

1.51

5.55e-05

GO:1901605

Alpha-amino acid metabolic process

7 of 139

1.22

1.29

5.55e-05

GO:0009084

Glutamine family amino acid biosynthetic process

3 of 23

1.63

1.07

0.0057

GO:0006082

Organic acid metabolic process

8 of 363

0.86

0.75

0.00036

GO:0006536

Glutamate metabolic process

2 of 9

1.87

0.75

0.0376

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2032

Cellular amino acid biosynthetic process, and Vitamin binding

7 of 117

1.3

1.52

1.08e-05

CL:2167

Valine, leucine and isoleucine biosynthesis, and Cysteine and methionine metabolism

4 of 47

1.45

1.09

0.0029

CL:1539

Mixed, incl. Pyruvate ferredoxin/flavodoxin oxidoreductase, and 3Fe-4S

2 of 6

2.04

0.8

0.0314

CL:1514

Mixed, incl. Citrate cycle (TCA cycle), and Aldehyde dehydrogenase domain

4 of 84

1.2

0.71

0.0189

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01230

Biosynthesis of amino acids

8 of 159

1.22

1.59

3.00e-07

map00250

Alanine, aspartate and glutamate metabolism

3 of 27

1.56

1.18

0.0025

map01110

Biosynthesis of secondary metabolites

9 of 440

0.83

0.8

1.65e-05

map01100

Metabolic pathways

11 of 1399

0.41

0.35

0.0012

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0028

Amino-acid biosynthesis

4 of 66

1.3

0.87

0.0083

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01558

Pyruvate ferredoxin/flavodoxin oxidoreductase

2 of 2

2.52

0.84

0.0296

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR019752

Pyruvate/ketoisovalerate oxidoreductase, catalytic domain

2 of 2

2.52

0.76

0.0410

IPR002880

Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain

2 of 2

2.52

0.76

0.0410

IPR002869

Pyruvate-flavodoxin oxidoreductase, central domain

2 of 2

2.52

0.76

0.0410

IPR029061

Thiamin diphosphate-binding fold

3 of 18

1.74

0.72

0.0410

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