STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEW24706.1PFAM: aminotransferase class I and II; KEGG: dsh:Dshi_2088 histidinol-phosphate aminotransferase. (368 aa)    
Predicted Functional Partners:
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: sil:SPO1163 imidazoleglycerol-phosphate dehydratase.
 
 0.989
EEW24685.1
PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pde:Pden_1408 cyclohexadienyl dehydrogenase.
  
 
 0.952
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
 
 0.899
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
 0.887
EEW24791.1
PFAM: aminotransferase class IV; KEGG: rde:RD1_1004 D-alanine aminotransferase.
   
 
  0.883
EEW26982.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: dsh:Dshi_0653 prephenate dehydratase.
  
 
 0.882
EEW25427.1
PFAM: aminotransferase class I and II; KEGG: dsh:Dshi_0762 aspartate aminotransferase.
  
 
  0.877
EEW24118.1
Aromatic-amino-acid transaminase; PFAM: aminotransferase class I and II; KEGG: rde:RD1_0935 aromatic amino acid aminotransferase.
   
 
 0.861
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 
 0.857
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
  
 0.848
Your Current Organism:
Rhodobacter sp. SW2
NCBI taxonomy Id: 371731
Other names: R. sp. SW2, Rhodobacter sp. SW 2
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