node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW24224.1 | EEW24225.1 | Rsw2DRAFT_2844 | Rsw2DRAFT_2845 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | 0.672 |
EEW24224.1 | EEW24271.1 | Rsw2DRAFT_2844 | Rsw2DRAFT_2787 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | 0.406 |
EEW24225.1 | EEW24224.1 | Rsw2DRAFT_2845 | Rsw2DRAFT_2844 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.672 |
EEW24225.1 | EEW24271.1 | Rsw2DRAFT_2845 | Rsw2DRAFT_2787 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | 0.645 |
EEW24225.1 | EEW26614.1 | Rsw2DRAFT_2845 | Rsw2DRAFT_0417 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.852 |
EEW24225.1 | EEW27017.1 | Rsw2DRAFT_2845 | Rsw2DRAFT_0252 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | KEGG: sil:SPO0107 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: DEAD-like helicases; helicase domain protein; HRDC domain protein. | 0.689 |
EEW24225.1 | ligA | Rsw2DRAFT_2845 | Rsw2DRAFT_2761 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.759 |
EEW24225.1 | mutL | Rsw2DRAFT_2845 | Rsw2DRAFT_0497 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.880 |
EEW24225.1 | polA | Rsw2DRAFT_2845 | Rsw2DRAFT_2921 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.736 |
EEW24225.1 | recA | Rsw2DRAFT_2845 | Rsw2DRAFT_0628 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.887 |
EEW24225.1 | uvrB | Rsw2DRAFT_2845 | Rsw2DRAFT_1322 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.904 |
EEW24225.1 | uvrC | Rsw2DRAFT_2845 | Rsw2DRAFT_2416 | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.661 |
EEW24271.1 | EEW24224.1 | Rsw2DRAFT_2787 | Rsw2DRAFT_2844 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.406 |
EEW24271.1 | EEW24225.1 | Rsw2DRAFT_2787 | Rsw2DRAFT_2845 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | PFAM: UvrD/REP helicase; KEGG: sil:SPO1174 DNA helicase II, putative. | 0.645 |
EEW24271.1 | EEW26614.1 | Rsw2DRAFT_2787 | Rsw2DRAFT_0417 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
EEW24271.1 | EEW27017.1 | Rsw2DRAFT_2787 | Rsw2DRAFT_0252 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | KEGG: sil:SPO0107 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: DEAD-like helicases; helicase domain protein; HRDC domain protein. | 0.932 |
EEW24271.1 | ligA | Rsw2DRAFT_2787 | Rsw2DRAFT_2761 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.823 |
EEW24271.1 | mutL | Rsw2DRAFT_2787 | Rsw2DRAFT_0497 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.980 |
EEW24271.1 | polA | Rsw2DRAFT_2787 | Rsw2DRAFT_2921 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
EEW24271.1 | recA | Rsw2DRAFT_2787 | Rsw2DRAFT_0628 | KEGG: rde:RD1_3542 ATP-dependent DNA helicase, UvrD/REP family domain; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; UvrD/REP helicase; SMART: DEAD-like helicases; helicase domain protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.991 |