Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsYSignal recognition particle receptor; COG_category U;COG_number COG0552; FtsY. (346 aa)    
Predicted Functional Partners:
ffh
Protein component of signal recognition particle (SRP); COG_category U;COG_number COG0541; Ffh.
 
0.998
secE
Preprotein translocase IISP family, membrane subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.
    
 0.987
secY
Membrane-embebed preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 0.979
yidC
Preprotein translocase, membrane component; COG_category U;COG_number COG0707; YidC.
   
 
 0.972
secA
Preprotein translocase subunit (ATPase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity); Belongs to the SecA family.
     
 0.968
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.910
rplQ
50S ribosomal protein L17; COG_category J;COG_number COG0203; RplQ; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.907
secG
Preprotein translocase IISP family, auxillary membrane component; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
     
  0.900
rpmG
50S ribosomal protein L33; COG_category J;COG_number COG0267; RpmG; Belongs to the bacterial ribosomal protein bL33 family.
   
 
 0.899
rpmB
50S ribosomal protein L28; COG_category J;COG_number COG0227; RpmB; Belongs to the bacterial ribosomal protein bL28 family.
   
 
 0.898
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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