STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycfHPutative deoxyribonuclease, tatD family; COG_category L;COG_number COG0084; YcfH. (264 aa)    
Predicted Functional Partners:
holB
DNA polymerase III, d' subunit; COG_category L;COG_number COG0470; HolB.
 
    0.913
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
 0.868
metG
methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family.
   0.857
fabD
Malonyl CoA-acyl carrier protein transacylase; COG_category I;COG_number COG0331; FabD.
      0.840
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
       0.666
fabG
3-oxoacyl-(acyl-carrier protein) reductase; COG_category Q;COG_number COG1028; FabG.
      0.658
polA
5'-3' exonuclease domain of DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
     0.570
cysS
cysteinyl-tRNA synthetase; COG_category J; CysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.477
nuoCD
NADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
       0.447
dnaX
DNA polymerase III, g and t subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.444
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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