STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asdAspartate-semialdehyde dehydrogenase; COG_category E;COG_number COG0136; Asd; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa)    
Predicted Functional Partners:
thrA
Aspartokinase I / homoserine dehydrogenase I; COG_category E;COG_number COG0460, COG0527; ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.999
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.965
thrC
Threonine synthase; COG_category E;COG_number COG0498; ThrC.
  
 
 0.963
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.963
pgk
Phosphoglycerate kinase; COG_category G;COG_number COG0126; Pgk; Belongs to the phosphoglycerate kinase family.
  
   0.828
hisB
Imidazoleglycerol-phosphate dehydratase; COG_category E;COG_number COG0131, COG0241; HisB; In the N-terminal section; belongs to the histidinol- phosphatase family.
     
 0.812
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
  
 0.792
pheA
Bifunctional chorismate mutase P/prephenate dehydratase; COG_category E;COG_number COG0077, COG1605; mutase N-terminal domain and dehydratase C-terminal domain; PheA.
     
 0.714
polA
5'-3' exonuclease domain of DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.631
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.598
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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