Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yheMUncharacterized conserved protein; COG_category P;COG_number COG2923; YheM; Belongs to the DsrF/TusC family. (119 aa)    
Predicted Functional Partners:
yheL
Uncharacterized conserved protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
 0.999
yheN
Uncharacterized conserved protein; COG_category P;COG_number COG1553; YheN.
 
 0.999
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
       0.744
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
       0.721
yrbA
Putative transcriptional regulator, bolA family; COG_category R;COG_number COG5007; YrbA.
  
     0.690
mesJ
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
     0.685
zapA
Conserved protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
     0.615
yaeT
Outer membrane protein precursor; COG_category J;COG_number COG4775; YaeT.
  
     0.611
bioH
Carboxylesterase; COG_category R;COG_number COG0596; BioH.
 
     0.599
yhhP
Small ubiquitous protein; COG_category O;COG_number COG0425; required for normal growth; YhhP; Belongs to the sulfur carrier protein TusA family.
 
   
 0.561
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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