node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaS | metG | BCc_254 | BCc_072 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.927 |
alaS | yqgF | BCc_254 | BCc_360 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | Putative Holliday jonction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.629 |
cca | metG | BCc_038 | BCc_072 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.704 |
cca | rpmF | BCc_038 | BCc_215 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 50S ribosomal protein L32; COG_category J;COG_number COG0333; RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.753 |
cca | yggX | BCc_038 | BCc_363 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Protection of iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.600 |
cca | yqgF | BCc_038 | BCc_360 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Putative Holliday jonction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.504 |
metG | alaS | BCc_072 | BCc_254 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.927 |
metG | cca | BCc_072 | BCc_038 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.704 |
metG | miaA | BCc_072 | BCc_371 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.460 |
metG | mutY | BCc_072 | BCc_362 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | 0.424 |
metG | rpmF | BCc_072 | BCc_215 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | 50S ribosomal protein L32; COG_category J;COG_number COG0333; RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.829 |
metG | yqgF | BCc_072 | BCc_360 | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative Holliday jonction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.609 |
miaA | metG | BCc_371 | BCc_072 | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.460 |
miaA | yqgF | BCc_371 | BCc_360 | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Putative Holliday jonction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.535 |
mutY | metG | BCc_362 | BCc_072 | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.424 |
mutY | rimM | BCc_362 | BCc_247 | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | 16s rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.538 |
mutY | yggW | BCc_362 | BCc_361 | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | Putative oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.530 |
mutY | yggX | BCc_362 | BCc_363 | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | Protection of iron-sulfur proteins against oxidative damage; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.978 |
mutY | yqgF | BCc_362 | BCc_360 | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | Putative Holliday jonction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.879 |
rimM | mutY | BCc_247 | BCc_362 | 16s rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | A/G-specific adenine glycosylase; COG_category L;COG_number COG1194; MutY. | 0.538 |