Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
miaADelta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (312 aa)    
Predicted Functional Partners:
miaB
Bifunctional enzyme involved in thiolation and methylation of tRNA; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
 0.968
pheT
phenylalanyl-tRNA synthetase, b subunit; COG_category J;COG_number COG0072; PheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.892
pheA
Bifunctional chorismate mutase P/prephenate dehydratase; COG_category E;COG_number COG0077, COG1605; mutase N-terminal domain and dehydratase C-terminal domain; PheA.
  
  
 0.812
ftsJ
Ribosomal methytransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
  
 0.736
trmD
tRNA (guanine-n1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
  
 0.631
metG
methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.618
thrA
Aspartokinase I / homoserine dehydrogenase I; COG_category E;COG_number COG0460, COG0527; ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
       0.558
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
  
 0.521
fabZ
(3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase; COG_category I;COG_number COG0764; FabZ.
     
 0.518
truA
Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.514
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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