SERPINA5 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F2	PLAT	ENSANAP00000038935	ENSANAP00000034934	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator; Belongs to the peptidase S1 family.	0.740
F2	PLAU	ENSANAP00000038935	ENSANAP00000031177	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator, urokinase.	0.557
F2	PROC	ENSANAP00000038935	ENSANAP00000015898	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.991
F2	SERPINA5	ENSANAP00000038935	ENSANAP00000000075	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family A member 5; Belongs to the serpin family.	0.886
F2	SERPINB2	ENSANAP00000038935	ENSANAP00000006786	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family B member 2; Belongs to the serpin family.	0.696
F2	SERPINC1	ENSANAP00000038935	ENSANAP00000038957	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.999
F2	SERPINE2	ENSANAP00000038935	ENSANAP00000032430	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family E member 2; Belongs to the serpin family.	0.976
F2	VTN	ENSANAP00000038935	ENSANAP00000000180	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SMB domain-containing protein.	0.906
PLAT	F2	ENSANAP00000034934	ENSANAP00000038935	Plasminogen activator; Belongs to the peptidase S1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.740
PLAT	PLAU	ENSANAP00000034934	ENSANAP00000031177	Plasminogen activator; Belongs to the peptidase S1 family.	Plasminogen activator, urokinase.	0.538
PLAT	SERPINA5	ENSANAP00000034934	ENSANAP00000000075	Plasminogen activator; Belongs to the peptidase S1 family.	Serpin family A member 5; Belongs to the serpin family.	0.932
PLAT	SERPINB2	ENSANAP00000034934	ENSANAP00000006786	Plasminogen activator; Belongs to the peptidase S1 family.	Serpin family B member 2; Belongs to the serpin family.	0.958
PLAT	SERPINC1	ENSANAP00000034934	ENSANAP00000038957	Plasminogen activator; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.627
PLAT	SERPINE2	ENSANAP00000034934	ENSANAP00000032430	Plasminogen activator; Belongs to the peptidase S1 family.	Serpin family E member 2; Belongs to the serpin family.	0.991
PLAT	TFPI2	ENSANAP00000034934	ENSANAP00000035583	Plasminogen activator; Belongs to the peptidase S1 family.	Tissue factor pathway inhibitor.	0.526
PLAT	VTN	ENSANAP00000034934	ENSANAP00000000180	Plasminogen activator; Belongs to the peptidase S1 family.	SMB domain-containing protein.	0.612
PLAU	F2	ENSANAP00000031177	ENSANAP00000038935	Plasminogen activator, urokinase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.557
PLAU	PLAT	ENSANAP00000031177	ENSANAP00000034934	Plasminogen activator, urokinase.	Plasminogen activator; Belongs to the peptidase S1 family.	0.538
PLAU	SERPINA5	ENSANAP00000031177	ENSANAP00000000075	Plasminogen activator, urokinase.	Serpin family A member 5; Belongs to the serpin family.	0.963
PLAU	SERPINB2	ENSANAP00000031177	ENSANAP00000006786	Plasminogen activator, urokinase.	Serpin family B member 2; Belongs to the serpin family.	0.986