STAM2 protein (Aotus nancymaae) - STRING interaction network

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Score

STAM2

Signal transducing adaptor molecule 2. (525 aa)

Predicted Functional Partners:

HGS

0.991

STAM

0.984

STAMBP

0.975

ITSN1

0.960

ITSN2

0.960

USP8

0.953

STAMBPL1

0.946

JAK3

0.934

ZFYVE1

0.933

ZFYVE19

0.933

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HGS	ITSN1	ENSANAP00000006705	ENSANAP00000015261	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 1.	0.959
HGS	ITSN2	ENSANAP00000006705	ENSANAP00000032932	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 2.	0.961
HGS	STAM	ENSANAP00000006705	ENSANAP00000019442	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.997
HGS	STAM2	ENSANAP00000006705	ENSANAP00000000097	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule 2.	0.991
HGS	USP8	ENSANAP00000006705	ENSANAP00000041236	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.909
ITSN1	HGS	ENSANAP00000015261	ENSANAP00000006705	Intersectin 1.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.959
ITSN1	ITSN2	ENSANAP00000015261	ENSANAP00000032932	Intersectin 1.	Intersectin 2.	0.964
ITSN1	STAM	ENSANAP00000015261	ENSANAP00000019442	Intersectin 1.	Signal transducing adaptor molecule.	0.960
ITSN1	STAM2	ENSANAP00000015261	ENSANAP00000000097	Intersectin 1.	Signal transducing adaptor molecule 2.	0.960
ITSN1	ZFYVE1	ENSANAP00000015261	ENSANAP00000003013	Intersectin 1.	Zinc finger FYVE-type containing 1.	0.959
ITSN1	ZFYVE19	ENSANAP00000015261	ENSANAP00000037125	Intersectin 1.	Zinc finger FYVE-type containing 19.	0.959
ITSN2	HGS	ENSANAP00000032932	ENSANAP00000006705	Intersectin 2.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.961
ITSN2	ITSN1	ENSANAP00000032932	ENSANAP00000015261	Intersectin 2.	Intersectin 1.	0.964
ITSN2	JAK3	ENSANAP00000032932	ENSANAP00000001288	Intersectin 2.	Tyrosine-protein kinase.	0.546
ITSN2	STAM	ENSANAP00000032932	ENSANAP00000019442	Intersectin 2.	Signal transducing adaptor molecule.	0.960
ITSN2	STAM2	ENSANAP00000032932	ENSANAP00000000097	Intersectin 2.	Signal transducing adaptor molecule 2.	0.960
ITSN2	ZFYVE1	ENSANAP00000032932	ENSANAP00000003013	Intersectin 2.	Zinc finger FYVE-type containing 1.	0.961
ITSN2	ZFYVE19	ENSANAP00000032932	ENSANAP00000037125	Intersectin 2.	Zinc finger FYVE-type containing 19.	0.961
JAK3	ITSN2	ENSANAP00000001288	ENSANAP00000032932	Tyrosine-protein kinase.	Intersectin 2.	0.546
JAK3	STAM	ENSANAP00000001288	ENSANAP00000019442	Tyrosine-protein kinase.	Signal transducing adaptor molecule.	0.934