Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSANAP00000000098Uncharacterized protein. (91 aa)    
Predicted Functional Partners:
EIF5A
Eukaryotic translation initiation factor 5A.
    
 
 0.802
EIF5A2
Eukaryotic translation initiation factor 5A.
    
 
 0.712
LOC105730568
Uncharacterized protein.
    
 
 0.697
THOC2
Uncharacterized protein.
    
 
 0.697
UTRN
Utrophin.
    
 
 0.666
ENSANAP00000004512
Uncharacterized protein.
    
   0.521
ATM
Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]
   
    0.521
THOC1
Death domain-containing protein.
    
   0.521
ENSANAP00000006142
Uncharacterized protein.
    
   0.494
THOC5
Uncharacterized protein.
    
   0.494
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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