Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa)    
Predicted Functional Partners:
EIF3B
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 0.854
ITSN2
Intersectin 2.
    
 0.835
RPS9
Ribosomal protein S9.
   
  0.804
ENSANAP00000004482
Ribosomal_S4 domain-containing protein.
   
  0.804
RPS21
40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
    
  0.797
LOC105730106
Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.
    
  0.795
ENSANAP00000040584
Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.
    
  0.795
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.787
ENSANAP00000042039
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.787
RPS3A
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
    
  0.779
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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