STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)    
Predicted Functional Partners:
IFNGR1
Interferon gamma receptor 1.
  
 
 0.996
IFNGR2
Interferon gamma receptor 2.
    
 0.993
IL10
Interleukin 10.
   
  
 0.957
IFNAR1
Interferon alpha and beta receptor subunit 1.
     
 0.957
JAK1
Tyrosine-protein kinase.
     
 0.957
JAK2
Tyrosine-protein kinase.
   
 
 0.941
IL2RA
Interleukin 2 receptor subunit alpha.
   
 
 0.926
PSME1
Proteasome activator subunit 1.
   
 
 0.904
ENSANAP00000016151
Uncharacterized protein.
   
 
 0.904
IL6
Interleukin 6.
   
 
 0.903
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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