Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (627 aa)    
Predicted Functional Partners:
CHRNB2
Cholinergic receptor nicotinic beta 2 subunit.
  
0.998
CHRNB3
Cholinergic receptor nicotinic beta 3 subunit.
  
 
0.984
CHRNA6
Cholinergic receptor nicotinic alpha 6 subunit.
  
 
0.981
CHRNB4
Cholinergic receptor nicotinic beta 4 subunit.
  
0.970
CHRNA5
Cholinergic receptor nicotinic alpha 5 subunit.
  
 
0.954
LYNX1
Ly6/neurotoxin 1.
    
 0.920
JAK2
Tyrosine-protein kinase.
     
  0.900
CHRNA3
Cholinergic receptor nicotinic alpha 3 subunit.
  
 
0.846
CHRND
Cholinergic receptor nicotinic delta subunit.
    
 
0.837
CLDN18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.800
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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