Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIMC1SUMO interacting motifs containing 1. (881 aa)    
Predicted Functional Partners:
SMC6
Structural maintenance of chromosomes 6.
    
   0.789
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
    
   0.773
WASHC2C
CAP-ZIP_m domain-containing protein.
    
 
 0.746
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.642
RAB24
RAB24, member RAS oncogene family.
    
 0.469
MC1R
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.456
GNS
Glucosamine (N-acetyl)-6-sulfatase.
    
 
 0.451
DDX23
DEAD-box helicase 23.
    
 0.413
RANBP2
RAN binding protein 2.
    
 0.410
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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