STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (225 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.992
JAK3
Tyrosine-protein kinase.
   
 0.985
JAK1
Tyrosine-protein kinase.
   
 0.985
TYK2
Tyrosine-protein kinase.
   
 0.980
STAT1
Signal transducer and activator of transcription.
   
 0.962
LEPR
Leptin receptor.
    
 0.957
STAT2
Signal transducer and activator of transcription.
   
 0.955
STAT3
Signal transducer and activator of transcription.
   
 0.952
CSF3R
Colony stimulating factor 3 receptor.
   
 0.945
INSR
Tyrosine-protein kinase receptor.
    
 0.941
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.