Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (225 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.999
JAK1
Tyrosine-protein kinase.
    
 0.994
JAK3
Tyrosine-protein kinase.
   
 0.993
TYK2
Tyrosine-protein kinase.
    
 0.992
STAT1
Signal transducer and activator of transcription.
   
 0.990
STAT3
Signal transducer and activator of transcription.
   
 0.990
LEPR
Leptin receptor.
    
 0.986
IRS1
Insulin receptor substrate 1.
    
 0.986
SOCS1
Suppressor of cytokine signaling 1.
   
 
0.986
INSR
Tyrosine-protein kinase receptor.
    
 0.982
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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