Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND6BDENN domain containing 6B. (580 aa)    
Predicted Functional Partners:
RUSC2
RUN and SH3 domain containing 2.
      
 0.601
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2.
      
 0.599
PRORP
PRORP domain-containing protein.
      
 0.542
ATP6V1F
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.491
OCRL
OCRL inositol polyphosphate-5-phosphatase.
      
 0.466
SDK2
Sidekick cell adhesion molecule 2.
      
 0.464
SDK1
Sidekick cell adhesion molecule 1.
      
 0.463
UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats.
      
 0.463
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif 6.
      
 0.433
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif 10.
      
 0.433
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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