PLCB4 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PLCB4

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)

Predicted Functional Partners:

GNA14

0.943

GNA15

0.929

PRKCA

0.925

GNAQ

0.924

GNA11

0.924

GNAI1

0.919

GNAI2

0.919

PRKCG

0.916

PRKCB

0.916

GNAT3

0.912

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA11	GNA15	ENSANAP00000030586	ENSANAP00000023403	G protein subunit alpha 11.	G protein subunit alpha 15.	0.519
GNA11	PLCB4	ENSANAP00000030586	ENSANAP00000001151	G protein subunit alpha 11.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.924
GNA14	GNA15	ENSANAP00000003344	ENSANAP00000023403	G protein subunit alpha 14.	G protein subunit alpha 15.	0.519
GNA14	PLCB4	ENSANAP00000003344	ENSANAP00000001151	G protein subunit alpha 14.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.943
GNA15	GNA11	ENSANAP00000023403	ENSANAP00000030586	G protein subunit alpha 15.	G protein subunit alpha 11.	0.519
GNA15	GNA14	ENSANAP00000023403	ENSANAP00000003344	G protein subunit alpha 15.	G protein subunit alpha 14.	0.519
GNA15	GNAQ	ENSANAP00000023403	ENSANAP00000004849	G protein subunit alpha 15.	G protein subunit alpha q.	0.519
GNA15	PLCB4	ENSANAP00000023403	ENSANAP00000001151	G protein subunit alpha 15.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.929
GNAI1	GNAI2	ENSANAP00000016314	ENSANAP00000032476	G protein subunit alpha i1.	G protein subunit alpha i2.	0.970
GNAI1	GNAT3	ENSANAP00000016314	ENSANAP00000006218	G protein subunit alpha i1.	G protein subunit alpha transducin 3.	0.503
GNAI1	PLCB4	ENSANAP00000016314	ENSANAP00000001151	G protein subunit alpha i1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.919
GNAI1	PRKCA	ENSANAP00000016314	ENSANAP00000032390	G protein subunit alpha i1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.745
GNAI1	PRKCB	ENSANAP00000016314	ENSANAP00000019904	G protein subunit alpha i1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.745
GNAI1	PRKCG	ENSANAP00000016314	ENSANAP00000011209	G protein subunit alpha i1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.737
GNAI2	GNAI1	ENSANAP00000032476	ENSANAP00000016314	G protein subunit alpha i2.	G protein subunit alpha i1.	0.970
GNAI2	GNAT3	ENSANAP00000032476	ENSANAP00000006218	G protein subunit alpha i2.	G protein subunit alpha transducin 3.	0.573
GNAI2	PLCB4	ENSANAP00000032476	ENSANAP00000001151	G protein subunit alpha i2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.919
GNAI2	PRKCA	ENSANAP00000032476	ENSANAP00000032390	G protein subunit alpha i2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.782
GNAI2	PRKCB	ENSANAP00000032476	ENSANAP00000019904	G protein subunit alpha i2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.771
GNAI2	PRKCG	ENSANAP00000032476	ENSANAP00000011209	G protein subunit alpha i2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.763

page 1 of 3

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About