STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HTRA4HtrA serine peptidase 4. (476 aa)    
Predicted Functional Partners:
SCP2
Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.959
XIAP
X-linked inhibitor of apoptosis.
    
 0.851
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.836
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.797
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.740
TNFRSF1A
TNF receptor superfamily member 1A.
    
 
 0.716
PINK1
PTEN induced kinase 1.
    
 0.696
LOC105713290
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.673
PSMC4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
    
 0.673
PSMC6
AAA domain-containing protein; Belongs to the AAA ATPase family.
    
 0.673
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.