Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSANAP00000001182Uncharacterized protein. (56 aa)    
Predicted Functional Partners:
ENSANAP00000011104
SCA7 domain-containing protein.
    
 0.931
ATXN7L3
Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]
    
 0.931
TADA2B
Transcriptional adapter.
    
 0.925
SUPT3H
SPT3 homolog, SAGA and STAGA complex component.
    
 0.923
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
   
 0.923
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.921
KAT2A
Lysine acetyltransferase 2A.
    
 0.918
SUPT20H
SPT20 homolog, SAGA complex component.
    
 0.918
TAF12
TATA-box binding protein associated factor 12.
   
 0.918
TADA3
Transcriptional adaptor 3.
    
 0.917
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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