Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.917
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1.
    
 0.827
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.797
AKR1D1
Aldo-keto reductase family 1 member D1.
    
 
 0.791
DIRAS2
DIRAS family GTPase 2.
   
   0.700
RNF19B
RBR-type E3 ubiquitin transferase.
    
   0.660
CCNY
Cyclin Y; Belongs to the cyclin family.
      
 0.616
ITSN2
Intersectin 2.
    
 0.615
LRRC17
Leucine rich repeat containing 17.
    
 0.606
RAP1GAP
RAP1 GTPase activating protein.
    
 0.587
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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