Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
PHACTR1Phosphatase and actin regulator. (607 aa)    
Predicted Functional Partners:
ACTG2
Actin gamma 2, smooth muscle.
    
   0.792
ACTA1
Actin alpha 1, skeletal muscle.
    
   0.706
MEGF11
Multiple EGF like domains 11.
      
 0.685
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
      
 0.654
CHRM2
Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
      
 0.638
MRTFB
Myocardin related transcription factor B.
      
 0.626
RHBDF1
Rhomboid 5 homolog 1.
      
 0.625
MPZL3
Myelin protein zero like 3.
      
 0.625
WSCD2
WSC domain containing 2.
      
 0.622
REEP1
Receptor expression-enhancing protein.
      
 0.622
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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