DDX5 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DDX5

DEAD-box helicase 5; Belongs to the DEAD box helicase family. (661 aa)

Predicted Functional Partners:

DROSHA

0.979

SF3B1

0.950

DHX9

0.936

DDX17

0.922

ESR1

0.908

RBM39

0.901

ENSANAP00000042215

0.901

DKC1

0.867

SON

0.866

PES1-2

0.860

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX17	DDX5	ENSANAP00000035084	ENSANAP00000001239	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.922
DDX17	DHX9	ENSANAP00000035084	ENSANAP00000025209	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	DExH-box helicase 9.	0.836
DDX17	DKC1	ENSANAP00000035084	ENSANAP00000009502	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Dyskerin pseudouridine synthase 1.	0.867
DDX17	DROSHA	ENSANAP00000035084	ENSANAP00000005466	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.901
DDX17	ENSANAP00000042215	ENSANAP00000035084	ENSANAP00000042215	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	RRM domain-containing protein.	0.668
DDX17	ESR1	ENSANAP00000035084	ENSANAP00000032641	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.845
DDX17	PES1-2	ENSANAP00000035084	ENSANAP00000007056	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.860
DDX17	RBM39	ENSANAP00000035084	ENSANAP00000013557	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	RNA binding motif protein 39.	0.668
DDX17	SF3B1	ENSANAP00000035084	ENSANAP00000007096	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	Splicing factor 3b subunit 1.	0.861
DDX17	SON	ENSANAP00000035084	ENSANAP00000035842	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	SON DNA binding protein.	0.477
DDX5	DDX17	ENSANAP00000001239	ENSANAP00000035084	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	DEAD-box helicase 17; Belongs to the DEAD box helicase family.	0.922
DDX5	DHX9	ENSANAP00000001239	ENSANAP00000025209	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	DExH-box helicase 9.	0.936
DDX5	DKC1	ENSANAP00000001239	ENSANAP00000009502	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Dyskerin pseudouridine synthase 1.	0.867
DDX5	DROSHA	ENSANAP00000001239	ENSANAP00000005466	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.979
DDX5	ENSANAP00000042215	ENSANAP00000001239	ENSANAP00000042215	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	RRM domain-containing protein.	0.901
DDX5	ESR1	ENSANAP00000001239	ENSANAP00000032641	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.908
DDX5	PES1-2	ENSANAP00000001239	ENSANAP00000007056	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.860
DDX5	RBM39	ENSANAP00000001239	ENSANAP00000013557	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	RNA binding motif protein 39.	0.901
DDX5	SF3B1	ENSANAP00000001239	ENSANAP00000007096	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Splicing factor 3b subunit 1.	0.950
DDX5	SON	ENSANAP00000001239	ENSANAP00000035842	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	SON DNA binding protein.	0.866