Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSANAP00000001243Protein S100; Belongs to the S-100 family. (105 aa)    
Predicted Functional Partners:
ANXA1
Annexin.
   
 
 0.794
ANXA2
Annexin.
   
 
 0.745
LOC105714560
Uncharacterized protein.
   
 
 0.745
S100A6
Protein S100; Belongs to the S-100 family.
   
  
 0.676
S100A8
Protein S100; Belongs to the S-100 family.
   
 0.601
S100A4
Protein S100; Belongs to the S-100 family.
   
  
 0.572
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
  0.499
S100A16
Protein S100; Belongs to the S-100 family.
  
  
 0.470
S100A1
Protein S100; Belongs to the S-100 family.
   
 0.469
S100A14
S100 calcium binding protein A14; Belongs to the S-100 family.
   
 
 0.454
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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