Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)    
Predicted Functional Partners:
H2BC18
Histone H2B; Belongs to the histone H2B family.
   
  0.954
H2AC6
Histone H2A; Belongs to the histone H2A family.
  
 0.939
H2AC20
Histone H2A; Belongs to the histone H2A family.
  
 0.923
H2AC7
Histone H2A; Belongs to the histone H2A family.
  
 0.873
LOC105726422
Histone H2B; Belongs to the histone H2B family.
   
  0.869
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.864
H2AJ
Histone H2A; Belongs to the histone H2A family.
  
 0.855
H2AC21
Histone H2A; Belongs to the histone H2A family.
  
 0.854
LOC105721506
Histone H2B; Belongs to the histone H2B family.
   
  0.833
H2BC21
Histone H2B; Belongs to the histone H2B family.
   
  0.830
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.