Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL22Kelch like family member 22. (634 aa)    
Predicted Functional Partners:
KLHL13
Kelch like family member 13.
    
  0.934
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.925
LOC105711628
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.925
KLHL26
Kelch like family member 26.
    
  0.841
UBXN7
UBX domain-containing protein 7.
    
 0.834
KLHL34
Kelch like family member 34.
    
  0.788
KLHL9
Kelch like family member 9.
    
  0.788
LOC105716995
RING-type domain-containing protein.
    
 0.771
ENSANAP00000019537
Zf-rbx1 domain-containing protein.
    
 0.771
RBX1
Ring-box 1.
    
 0.771
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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