Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFUncharacterized protein; Belongs to the transferrin family. (699 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor.
   
 0.988
ALB
Albumin.
   
  
 0.907
MIS12
MIS12 kinetochore complex component.
    
   0.893
TFR2
Transferrin receptor 2.
   
 0.880
LOC105706814
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
 0.865
SERPINA1
Serpin family A member 1; Belongs to the serpin family.
   
 
 0.754
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
   
 0.731
MAPT
Microtubule-associated protein.
    
 
 0.704
EPO
Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.
   
 0.662
AHSG
Alpha 2-HS glycoprotein.
   
  
 0.631
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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