STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFUncharacterized protein; Belongs to the transferrin family. (699 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor.
   
 0.996
TFR2
Transferrin receptor 2.
   
 0.856
MIS12
MIS12 kinetochore complex component.
    
   0.693
EPO
Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.
   
 0.683
CLU
Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
   
 0.618
ENSANAP00000012634
WAP domain-containing protein.
    
 0.579
CYB5R4
Cytochrome b5 reductase 4.
     
 0.562
ENSANAP00000035404
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
     
 0.562
LRP4
LDL receptor related protein 4.
     
 0.555
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.544
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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