EPHX4 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EPHX4

Epoxide hydrolase 4. (362 aa)

Predicted Functional Partners:

EPHX1

0.938

EPHX2

0.913

CYP1B1

0.909

EPHX3

0.903

LOC105710891

0.900

LOC105710841

0.900

AKR1A1

0.900

KCNAB1

0.743

KCNAB2

0.593

ECI2

0.534

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1A1	EPHX1	ENSANAP00000018032	ENSANAP00000019428	Aldo-keto reductase family 1 member A1.	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	0.907
AKR1A1	EPHX2	ENSANAP00000018032	ENSANAP00000000914	Aldo-keto reductase family 1 member A1.	Epoxide hydrolase 2.	0.909
AKR1A1	EPHX3	ENSANAP00000018032	ENSANAP00000016995	Aldo-keto reductase family 1 member A1.	Epoxide hydrolase 3.	0.900
AKR1A1	EPHX4	ENSANAP00000018032	ENSANAP00000001345	Aldo-keto reductase family 1 member A1.	Epoxide hydrolase 4.	0.900
AKR1A1	KCNAB1	ENSANAP00000018032	ENSANAP00000028680	Aldo-keto reductase family 1 member A1.	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	0.436
AKR1A1	KCNAB2	ENSANAP00000018032	ENSANAP00000017815	Aldo-keto reductase family 1 member A1.	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	0.439
AKR1A1	LOC105710841	ENSANAP00000018032	ENSANAP00000011523	Aldo-keto reductase family 1 member A1.	Aldo_ket_red domain-containing protein.	0.905
AKR1A1	LOC105710891	ENSANAP00000018032	ENSANAP00000005756	Aldo-keto reductase family 1 member A1.	Aldo_ket_red domain-containing protein.	0.904
CYP1B1	EPHX1	ENSANAP00000006842	ENSANAP00000019428	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	0.941
CYP1B1	EPHX2	ENSANAP00000006842	ENSANAP00000000914	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Epoxide hydrolase 2.	0.916
CYP1B1	EPHX3	ENSANAP00000006842	ENSANAP00000016995	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Epoxide hydrolase 3.	0.909
CYP1B1	EPHX4	ENSANAP00000006842	ENSANAP00000001345	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Epoxide hydrolase 4.	0.909
CYP1B1	LOC105710891	ENSANAP00000006842	ENSANAP00000005756	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Aldo_ket_red domain-containing protein.	0.903
ECI2	EPHX2	ENSANAP00000021968	ENSANAP00000000914	Enoyl-CoA delta isomerase 2.	Epoxide hydrolase 2.	0.951
ECI2	EPHX3	ENSANAP00000021968	ENSANAP00000016995	Enoyl-CoA delta isomerase 2.	Epoxide hydrolase 3.	0.534
ECI2	EPHX4	ENSANAP00000021968	ENSANAP00000001345	Enoyl-CoA delta isomerase 2.	Epoxide hydrolase 4.	0.534
EPHX1	AKR1A1	ENSANAP00000019428	ENSANAP00000018032	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Aldo-keto reductase family 1 member A1.	0.907
EPHX1	CYP1B1	ENSANAP00000019428	ENSANAP00000006842	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.941
EPHX1	EPHX2	ENSANAP00000019428	ENSANAP00000000914	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Epoxide hydrolase 2.	0.946
EPHX1	EPHX3	ENSANAP00000019428	ENSANAP00000016995	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Epoxide hydrolase 3.	0.939