Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DOLKDolichol kinase. (538 aa)    
Predicted Functional Partners:
DPM3
Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.
     
 0.964
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
    
 0.964
DOLPP1
Dolichyldiphosphatase 1.
  
 0.954
DPAGT1
Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1.
     
 0.950
ALG5
ALG5 dolichyl-phosphate beta-glucosyltransferase.
     
 0.941
CRLS1
Cardiolipin synthase 1.
   
 
 0.804
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
    
 0.780
SRD5A3
Steroid 5 alpha-reductase 3.
     
 0.760
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
 
 0.740
KCNA6
Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family.
    
   0.736
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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