Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LZTS2Leucine zipper tumor suppressor 2. (600 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.923
LZTS1
Leucine zipper tumor suppressor 1.
    
   0.824
SIPA1L1
Signal induced proliferation associated 1 like 1.
    
 
 0.798
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
    
 
 0.717
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.709
SIPA1L3
Signal induced proliferation associated 1 like 3.
    
 
 0.674
SIPA1
Signal-induced proliferation-associated 1.
    
 
 0.674
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.642
SIPA1L2
Signal induced proliferation associated 1 like 2.
    
 
 0.630
AFDN
Afadin, adherens junction formation factor.
    
 
 0.604
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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