Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSOCathepsin O; Belongs to the peptidase C1 family. (318 aa)    
Predicted Functional Partners:
BCL2L1
BCL2 like 1.
     
 0.903
BCL2
BCL2 apoptosis regulator.
     
  0.900
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
     
  0.900
BIRC3
Baculoviral IAP repeat containing 3.
     
 0.665
XIAP
X-linked inhibitor of apoptosis.
     
 0.655
BIRC2
Baculoviral IAP repeat containing 2.
     
 0.653
LOC105718674
Uncharacterized protein.
     
  0.650
LOC105719165
Abhydrolase_2 domain-containing protein.
    
   0.613
LYPLA1
Uncharacterized protein.
    
   0.613
GNB1L
G protein subunit beta 1 like.
      
 0.521
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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