STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MARCHF7Membrane associated ring-CH-type finger 7. (704 aa)    
Predicted Functional Partners:
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.855
TGFBR2
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
    
   0.781
USP7
Uncharacterized protein; Belongs to the peptidase C19 family.
    
 0.767
ENSANAP00000014529
USP7_C2 domain-containing protein.
    
 0.767
ENSANAP00000015998
Uncharacterized protein.
    
 0.767
ENSANAP00000006464
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.746
LOC110568879
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.746
ENSANAP00000039113
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.746
UBE2N
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.715
UBE2E1
Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.704
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.