Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (434 aa)    
Predicted Functional Partners:
NANS
N-acetylneuraminate synthase.
 
  
 0.995
NPL
N-acetylneuraminate pyruvate lyase; Belongs to the DapA family.
     
 0.944
NANP
N-acetylneuraminic acid phosphatase.
     
 0.944
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
   0.699
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit.
    
   0.687
LRRK2
Leucine rich repeat kinase 2.
    
   0.661
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.659
GAK
Cyclin G associated kinase.
     
 0.619
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.
      
 0.573
VPS26A
VPS26, retromer complex component A.
   
 
 0.544
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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