Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa)    
Predicted Functional Partners:
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
   
 0.996
KCNJ13
Potassium voltage-gated channel subfamily J member 13.
     
 0.936
KCNK5
Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.927
KCNN4
Potassium calcium-activated channel subfamily N member 4.
     
 0.926
LIPT1
Lipoyltransferase 1.
    
 0.778
KCNH2
Potassium voltage-gated channel subfamily H member 2.
     
 0.765
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
   
 0.742
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.716
KCNE4
Potassium voltage-gated channel subfamily E regulatory subunit 4.
      
 0.703
GCSH
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 0.690
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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