Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)    
Predicted Functional Partners:
ATF2
Activating transcription factor 2.
    
 
0.981
MAPK1
Mitogen-activated protein kinase.
    
 0.958
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.958
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
 0.951
CREBBP
CREB binding protein.
   
 0.948
EP300
E1A binding protein p300.
   
 0.948
CREB1
cAMP responsive element binding protein 1.
    
 0.938
ATF4
Activating transcription factor 4.
    
 0.935
PPARGC1A
PPARG coactivator 1 alpha.
     
 0.933
CREB3
cAMP responsive element binding protein 3.
     
 0.925
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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