TNFAIP8L1 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TNFAIP8L1

TNF alpha induced protein 8 like 1. (186 aa)

Predicted Functional Partners:

FBXW5

0.743

PGM2L1

0.540

C4orf45

0.540

LATS1

0.512

SMIM3

0.473

DNAJC1

0.465

LOC105717944

0.430

MED4

0.430

TMEM40

0.426

GPRIN1

0.415

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C4orf45	GPRIN1	ENSANAP00000022335	ENSANAP00000031121	Chromosome 4 open reading frame 45.	G protein regulated inducer of neurite outgrowth 1.	0.485
C4orf45	PGM2L1	ENSANAP00000022335	ENSANAP00000013363	Chromosome 4 open reading frame 45.	Phosphoglucomutase 2 like 1.	0.659
C4orf45	TNFAIP8L1	ENSANAP00000022335	ENSANAP00000001688	Chromosome 4 open reading frame 45.	TNF alpha induced protein 8 like 1.	0.540
DNAJC1	SMIM3	ENSANAP00000022469	ENSANAP00000001466	DnaJ heat shock protein family (Hsp40) member C1.	Small integral membrane protein 3.	0.467
DNAJC1	TMEM40	ENSANAP00000022469	ENSANAP00000038745	DnaJ heat shock protein family (Hsp40) member C1.	Transmembrane protein 40.	0.466
DNAJC1	TNFAIP8L1	ENSANAP00000022469	ENSANAP00000001688	DnaJ heat shock protein family (Hsp40) member C1.	TNF alpha induced protein 8 like 1.	0.465
FBXW5	TNFAIP8L1	ENSANAP00000041830	ENSANAP00000001688	F-box and WD repeat domain containing 5.	TNF alpha induced protein 8 like 1.	0.743
GPRIN1	C4orf45	ENSANAP00000031121	ENSANAP00000022335	G protein regulated inducer of neurite outgrowth 1.	Chromosome 4 open reading frame 45.	0.485
GPRIN1	PGM2L1	ENSANAP00000031121	ENSANAP00000013363	G protein regulated inducer of neurite outgrowth 1.	Phosphoglucomutase 2 like 1.	0.485
GPRIN1	TNFAIP8L1	ENSANAP00000031121	ENSANAP00000001688	G protein regulated inducer of neurite outgrowth 1.	TNF alpha induced protein 8 like 1.	0.415
LATS1	TNFAIP8L1	ENSANAP00000035740	ENSANAP00000001688	Large tumor suppressor kinase 1.	TNF alpha induced protein 8 like 1.	0.512
LOC105717944	MED4	ENSANAP00000013792	ENSANAP00000017712	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543
LOC105717944	TNFAIP8L1	ENSANAP00000013792	ENSANAP00000001688	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TNF alpha induced protein 8 like 1.	0.430
MED4	LOC105717944	ENSANAP00000017712	ENSANAP00000013792	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.543
MED4	TNFAIP8L1	ENSANAP00000017712	ENSANAP00000001688	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TNF alpha induced protein 8 like 1.	0.430
PGM2L1	C4orf45	ENSANAP00000013363	ENSANAP00000022335	Phosphoglucomutase 2 like 1.	Chromosome 4 open reading frame 45.	0.659
PGM2L1	GPRIN1	ENSANAP00000013363	ENSANAP00000031121	Phosphoglucomutase 2 like 1.	G protein regulated inducer of neurite outgrowth 1.	0.485
PGM2L1	TNFAIP8L1	ENSANAP00000013363	ENSANAP00000001688	Phosphoglucomutase 2 like 1.	TNF alpha induced protein 8 like 1.	0.540
SMIM3	DNAJC1	ENSANAP00000001466	ENSANAP00000022469	Small integral membrane protein 3.	DnaJ heat shock protein family (Hsp40) member C1.	0.467
SMIM3	TMEM40	ENSANAP00000001466	ENSANAP00000038745	Small integral membrane protein 3.	Transmembrane protein 40.	0.511