STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIGITT cell immunoreceptor with Ig and ITIM domains. (297 aa)    
Predicted Functional Partners:
NECTIN2
Nectin cell adhesion molecule 2.
    
 0.992
PVR
PVR cell adhesion molecule.
    
 0.985
NECTIN3
Nectin cell adhesion molecule 3.
    
 0.957
TOMM40L
Translocase of outer mitochondrial membrane 40 like.
    
 0.864
TOMM40
Translocase of outer mitochondrial membrane 40.
    
 0.864
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.727
LAG3
Lymphocyte activating 3.
   
  
 0.649
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
  
 0.617
BTLA
B and T lymphocyte associated.
   
  
 0.604
CD160
CD160 molecule.
   
  
 0.596
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.