Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIBP2PPFIA binding protein 2. (988 aa)    
Predicted Functional Partners:
PPFIBP1
PPFIA binding protein 1.
    
  0.896
TBC1D4
TBC1 domain family member 4.
    
   0.831
TBC1D1
TBC1 domain family member 1.
    
   0.831
CRK
CRK proto-oncogene, adaptor protein.
    
   0.795
PTPRS
Protein tyrosine phosphatase receptor type S.
     
 0.656
PTPRD
Protein tyrosine phosphatase receptor type D.
     
 0.645
PTPRF
Protein tyrosine phosphatase receptor type F.
     
 0.579
GLOD5
Glyoxalase domain containing 5.
      
 0.540
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
      
 0.517
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
   0.513
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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