| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRCA1 | TRIM28 | ENSANAP00000004329 | ENSANAP00000019076 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Tripartite motif containing 28. | 0.695 |
| BRCA1 | ZNF615 | ENSANAP00000004329 | ENSANAP00000001815 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Zinc finger protein 615. | 0.700 |
| TRIM28 | BRCA1 | ENSANAP00000019076 | ENSANAP00000004329 | Tripartite motif containing 28. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.695 |
| TRIM28 | ZNF248 | ENSANAP00000019076 | ENSANAP00000016882 | Tripartite motif containing 28. | Zinc finger protein 248. | 0.610 |
| TRIM28 | ZNF615 | ENSANAP00000019076 | ENSANAP00000001815 | Tripartite motif containing 28. | Zinc finger protein 615. | 0.795 |
| ZNF248 | TRIM28 | ENSANAP00000016882 | ENSANAP00000019076 | Zinc finger protein 248. | Tripartite motif containing 28. | 0.610 |
| ZNF248 | ZNF615 | ENSANAP00000016882 | ENSANAP00000001815 | Zinc finger protein 248. | Zinc finger protein 615. | 0.667 |
| ZNF461 | ZNF615 | ENSANAP00000002404 | ENSANAP00000001815 | Uncharacterized protein. | Zinc finger protein 615. | 0.728 |
| ZNF615 | BRCA1 | ENSANAP00000001815 | ENSANAP00000004329 | Zinc finger protein 615. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.700 |
| ZNF615 | TRIM28 | ENSANAP00000001815 | ENSANAP00000019076 | Zinc finger protein 615. | Tripartite motif containing 28. | 0.795 |
| ZNF615 | ZNF248 | ENSANAP00000001815 | ENSANAP00000016882 | Zinc finger protein 615. | Zinc finger protein 248. | 0.667 |
| ZNF615 | ZNF461 | ENSANAP00000001815 | ENSANAP00000002404 | Zinc finger protein 615. | Uncharacterized protein. | 0.728 |
