BRS3 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

BRS3

Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa)

Predicted Functional Partners:

GRP

0.990

NMB

0.976

GRPR

0.947

NMBR

0.934

GALK1

0.803

SEC11A

0.750

SEC11C

0.747

CCK

0.731

PFKL

0.715

GNG2

0.701

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRS3	CCK	ENSANAP00000001817	ENSANAP00000024823	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Cholecystokinin.	0.731
BRS3	GALK1	ENSANAP00000001817	ENSANAP00000039349	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Galactokinase 1.	0.803
BRS3	GNG2	ENSANAP00000001817	ENSANAP00000032214	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.701
BRS3	GRP	ENSANAP00000001817	ENSANAP00000009509	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Gastrin releasing peptide.	0.990
BRS3	GRPR	ENSANAP00000001817	ENSANAP00000007682	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.947
BRS3	NMB	ENSANAP00000001817	ENSANAP00000014990	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neuromedin B.	0.976
BRS3	NMBR	ENSANAP00000001817	ENSANAP00000003417	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.934
BRS3	PFKL	ENSANAP00000001817	ENSANAP00000008247	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.715
BRS3	SEC11A	ENSANAP00000001817	ENSANAP00000017790	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Signal peptidase complex catalytic subunit SEC11.	0.750
BRS3	SEC11C	ENSANAP00000001817	ENSANAP00000024993	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Signal peptidase complex catalytic subunit SEC11.	0.747
CCK	BRS3	ENSANAP00000024823	ENSANAP00000001817	Cholecystokinin.	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.731
CCK	GRP	ENSANAP00000024823	ENSANAP00000009509	Cholecystokinin.	Gastrin releasing peptide.	0.685
CCK	GRPR	ENSANAP00000024823	ENSANAP00000007682	Cholecystokinin.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.646
CCK	NMBR	ENSANAP00000024823	ENSANAP00000003417	Cholecystokinin.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.507
CCK	SEC11A	ENSANAP00000024823	ENSANAP00000017790	Cholecystokinin.	Signal peptidase complex catalytic subunit SEC11.	0.444
CCK	SEC11C	ENSANAP00000024823	ENSANAP00000024993	Cholecystokinin.	Signal peptidase complex catalytic subunit SEC11.	0.444
GALK1	BRS3	ENSANAP00000039349	ENSANAP00000001817	Galactokinase 1.	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.803
GALK1	GRPR	ENSANAP00000039349	ENSANAP00000007682	Galactokinase 1.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.517
GALK1	PFKL	ENSANAP00000039349	ENSANAP00000008247	Galactokinase 1.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.617
GNG2	BRS3	ENSANAP00000032214	ENSANAP00000001817	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.701