Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM170ATransmembrane protein 170A. (141 aa)    
Predicted Functional Partners:
KIAA1109
KIAA1109.
    
   0.660
MCPH1
Microcephalin 1.
      
 0.544
ENSANAP00000028003
SH3 domain-containing protein.
      
 0.523
BCAR1
SH3 domain-containing protein.
      
 0.523
LRIG2
Leucine rich repeats and immunoglobulin like domains 2.
      
 0.500
OSBPL3
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.465
NDC1
NDC1 transmembrane nucleoporin.
      
 0.463
ENSANAP00000008252
Uncharacterized protein.
      
 0.462
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
      
 0.462
C1orf43
Chromosome 1 open reading frame 43.
    
   0.455
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (16%) [HD]