PLEKHA7 protein (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PLEKHA7

Pleckstrin homology domain containing A7. (1286 aa)

Predicted Functional Partners:

CTNND1

0.832

CDH1

0.822

CTNNB1

0.803

YWHAB

0.747

KIFC3

0.723

ENSANAP00000023720

0.714

CTNNA1

0.714

ENSANAP00000029484

0.714

LOC105733239

0.714

YWHAQ

0.703

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH1	CTNNA1	ENSANAP00000021965	ENSANAP00000025141	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Catenin alpha 1.	0.989
CDH1	CTNNB1	ENSANAP00000021965	ENSANAP00000032405	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Catenin beta 1.	0.999
CDH1	CTNND1	ENSANAP00000021965	ENSANAP00000024431	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Catenin delta 1.	0.999
CDH1	ENSANAP00000023720	ENSANAP00000021965	ENSANAP00000023720	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.951
CDH1	ENSANAP00000029484	ENSANAP00000021965	ENSANAP00000029484	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.951
CDH1	LOC105733239	ENSANAP00000021965	ENSANAP00000031939	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.989
CDH1	PLEKHA7	ENSANAP00000021965	ENSANAP00000001909	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	Pleckstrin homology domain containing A7.	0.822
CTNNA1	CDH1	ENSANAP00000025141	ENSANAP00000021965	Catenin alpha 1.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.989
CTNNA1	CTNNB1	ENSANAP00000025141	ENSANAP00000032405	Catenin alpha 1.	Catenin beta 1.	0.993
CTNNA1	CTNND1	ENSANAP00000025141	ENSANAP00000024431	Catenin alpha 1.	Catenin delta 1.	0.952
CTNNA1	ENSANAP00000023720	ENSANAP00000025141	ENSANAP00000023720	Catenin alpha 1.	Uncharacterized protein.	0.543
CTNNA1	ENSANAP00000029484	ENSANAP00000025141	ENSANAP00000029484	Catenin alpha 1.	Uncharacterized protein.	0.549
CTNNA1	LOC105733239	ENSANAP00000025141	ENSANAP00000031939	Catenin alpha 1.	Uncharacterized protein.	0.545
CTNNA1	PLEKHA7	ENSANAP00000025141	ENSANAP00000001909	Catenin alpha 1.	Pleckstrin homology domain containing A7.	0.714
CTNNA1	YWHAB	ENSANAP00000025141	ENSANAP00000021278	Catenin alpha 1.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.693
CTNNA1	YWHAQ	ENSANAP00000025141	ENSANAP00000016574	Catenin alpha 1.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family.	0.689
CTNNB1	CDH1	ENSANAP00000032405	ENSANAP00000021965	Catenin beta 1.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.999
CTNNB1	CTNNA1	ENSANAP00000032405	ENSANAP00000025141	Catenin beta 1.	Catenin alpha 1.	0.993
CTNNB1	CTNND1	ENSANAP00000032405	ENSANAP00000024431	Catenin beta 1.	Catenin delta 1.	0.995
CTNNB1	ENSANAP00000023720	ENSANAP00000032405	ENSANAP00000023720	Catenin beta 1.	Uncharacterized protein.	0.956