Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CRLS1Cardiolipin synthase 1. (301 aa)    
Predicted Functional Partners:
CDS1
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
   
 0.985
CDS2
Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.
   
 0.985
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 0.961
PGS1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
    
 0.952
TAZ
Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism.
     
 0.949
LCLAT1
Lysocardiolipin acyltransferase 1.
  
 
 0.943
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.936
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
  
 
 0.936
LPGAT1
Lysophosphatidylglycerol acyltransferase 1.
  
 
 0.935
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
  
 
 0.920
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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