STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRLS1Cardiolipin synthase 1. (301 aa)    
Predicted Functional Partners:
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 0.947
PGS1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
    
 0.944
EPHX2
Epoxide hydrolase 2.
  
 
 0.938
CDS2
Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.
   
 0.932
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.931
LPGAT1
Lysophosphatidylglycerol acyltransferase 1.
  
 
 0.923
LCLAT1
Lysocardiolipin acyltransferase 1.
  
 
 0.914
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
  
 
 0.906
LPCAT2
Lysophosphatidylcholine acyltransferase 2.
  
 
 0.896
TAZ
Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism.
     
 0.891
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.