Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARCActivity regulated cytoskeleton associated protein. (398 aa)    
Predicted Functional Partners:
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 
 0.921
APP
Amyloid beta precursor protein.
    
 0.856
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.832
CAMK2B
Calcium/calmodulin dependent protein kinase II beta.
    
 
 0.797
RNF216
Ring finger protein 216.
    
 
 0.792
PSEN2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.765
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
    
 
 0.761
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
 
 0.751
DLG2
Discs large MAGUK scaffold protein 2.
   
 
 0.751
APLP2
Amyloid beta precursor like protein 2.
    
 0.709
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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