STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)    
Predicted Functional Partners:
ENSANAP00000019979
Fork-head domain-containing protein.
    
 0.923
CCNB1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
    
 0.923
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 0.915
ENSANAP00000034995
Uncharacterized protein; Belongs to the cyclin family.
    
 0.909
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 
 0.907
WWTR1
WW domain containing transcription regulator 1.
    
 0.895
LRRK2
Leucine rich repeat kinase 2.
   
 0.887
AMOT
Angiomotin.
    
 0.886
LOC105711962
MDM2 proto-oncogene.
    
 0.883
LOC105709408
RING-type domain-containing protein.
    
 0.883
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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